Author

Carlo Santambrogio

University of Milano-BicoccaORCID 0000-0003-3986-6971Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Alberta PinnolaiD· 1 shared Alberto BoldriniiD· 1 shared Alessandro GalbiatiiD· 1 shared Alexandros PatsilinakosiD· 1 shared Alice VetranoiD· 1 shared Andrea AstolfiiD· 1 shared C. RisueñoiD· 1 shared Carmine VarricchioiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Alberta PinnolaORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 25, 2026

Protein Folding Interference Enables Selective Cyclin D1 Degradation

Alessandro Galbiati, Enrica Colasurdo, Alexandros Patsilinakos…·Giovanni Spagnolli

This paper identifies a folding intermediate of Cyclin D1 as a target for selective degradation, showing that pharmacological interference with this state inhibits tumor growth and overcomes resistance to CDK4/6 inhibitors.

DOI 10.64898/2026.10.22.760876

humanprotein structure

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BiochemistryNature CommunicationsPeer-reviewedApr 16, 2025

Molecular Structure and Enzymatic Mechanism of the Human Collagen Hydroxylysine Galactosyltransferase GLT25D1/COLGALT1

Matteo De Marco, Sristi Rai Raj, Luigi Scietti…·Federico Forneris

This study characterizes the molecular structure and enzymatic mechanism of GLT25D1/COLGALT, identifying its catalytic site and dimeric assembly as critical for collagen lysine modification.

23 citationstop 3%

humanexperimental assay

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