John P. Russell

This study identifies SOX2+ sustentacular cells as stem cells for postnatal adrenal medulla chromaffin cells, showing their ability to generate both adrenaline and noradrenaline lineages and maintain homeostasis via WNT6 secretion.

The paper shows that pituitary stem cells secrete WNT signals that promote the proliferation of neighboring progenitor cells.

This study shows that the LATS/YAP/TAZ pathway regulates SOX2+ pituitary stem cells, controlling their homeostasis and tumourigenic potential during development and in adulthood.