Alice Santambrogio

This paper introduces scDynaBar, a method using CRISPR barcoding to track temporal cellular events at single-cell resolution, showing the transient nature of the 2C-like state in mESCs.

This study identifies SOX2+ cells in phaeochromocytomas and paragangliomas as potential tumour-initiating stem cells capable of expansion and metastasis.

This paper introduces a physics-based model explaining how cells maintain histone methylation patterns after division, validated by simulations and experimental data.

This study identifies SOX2+ sustentacular cells as stem cells for postnatal adrenal medulla chromaffin cells, showing their ability to generate both adrenaline and noradrenaline lineages and maintain homeostasis via WNT6 secretion.

The paper identifies epigenetically primed enhancers in early embryonic development and shows their role in regulating developmental gene networks across species.

The paper shows that pituitary stem cells secrete WNT signals that promote the proliferation of neighboring progenitor cells.

This study shows that the LATS/YAP/TAZ pathway regulates SOX2+ pituitary stem cells, controlling their homeostasis and tumourigenic potential during development and in adulthood.