Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells
John P. Russell, Xinhong Lim, Alice Santambrogio, Val Yianni, Yasmine Kemkem, Bruce Wang, M. Fish, Scott Haston, Anaëlle Grabek, Shirleen Hallang, Emily J. Lodge, Amanda L. Patist, Andreas Schedl, Patrice Mollard, Roeland Nusse, Cynthia L. Andoniadou
The paper shows that pituitary stem cells secrete WNT signals that promote the proliferation of neighboring progenitor cells.
eLife · Jan 5, 2021Peer-reviewedDevelopmental Biology