Author

Christian N. Cunningham

GenentechORCID 0000-0003-3993-660XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alix I ChaniD· 1 shared Althea Hansel-HarrisiD· 1 shared Anna ZhangiD· 1 shared Christina Helmling· 1 shared Clara FannjiangiD· 1 shared Emily C. WoodsiD· 1 shared Gabriele ScaliaiD· 1 shared Jeyun JoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Alix I ChanORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJul 22, 2025

Deep Evolutionary Fitness Inference for Variant Nomination from Directed Evolution

Max W. Shen, Nathaniel Diamant, Christina Helmling…·Tommaso Biancalani

This paper introduces EVFI and DeepEVFI, machine learning methods that infer variant fitness from directed evolution data, identifying tighter binders missed by conventional approaches.

DOI 10.1101/2025.07.22.666175

machine learning (classical)variant effect prediction

𝕏 PostBluesky

MicrobiologyJournal of the American Chemical SocietyPeer-reviewedFeb 27, 2025

An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor

Sijie Wang, Emily C. Woods, Jeyun Jo…·Matthew S. Bogyo

The paper develops fluorescent probes for FphB, a Staphylococcus aureus enzyme, using mRNA display with a genetically encoded electrophile, achieving nanomolar selectivity.

21 citationstop 3%

humanproteomics

𝕏 PostBluesky