Amy F. Lloyd

This study identifies glycogen metabolism as a key regulator of microglial function in Alzheimer's disease, showing that glycogenolysis drives microglial activation and that inhibiting it reduces Abeta uptake and functional impairment.

This study shows that older females have more inflammatory monocytes, which is reversed by Hormone Replacement Therapy.

This study shows neonatal microglia improve brain repair in aged mice through secreted factors, highlighting the potential of early microglial programs for regenerative therapies.

The paper introduces a proteomic tool to identify protein markers for human microglial states and validates their utility in purification and differentiation.

The paper compares proteomic profiles of human and mouse microglia from different sources, revealing significant differences between in vitro and ex vivo cultures.

The paper shows that astrocyte-oligodendrocyte interaction is critical for remyelination and identifies a drug strategy targeting this interaction to promote central nervous system regeneration.