Verity F. T. Mitchener

This study identifies TRPML1 loss as a cause of lysosomal calcium failure and astrocyte dysfunction in Alzheimer's Disease, showing that restoring TRPML1 can prevent disease progression.

This study identifies glycogen metabolism as a key regulator of microglial function in Alzheimer's disease, showing that glycogenolysis drives microglial activation and that inhibiting it reduces Abeta uptake and functional impairment.

The paper shows that sub-clinical doses of NMDA and AMPA glutamate receptor antagonists protect against demyelination in experimental models of multiple sclerosis.