Author
Ontario Institute for Cancer ResearchORCID 0000-0003-4013-118XUnclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Axel Levy, Rishwanth Raghu, J. Ryan Feathers…·Ellen D. Zhong
The paper introduces cryoDRGN-AI, a method for ab initio 3D reconstruction of cryo-EM and cryo-ET datasets, revealing new conformational states and unresolved motions.
Michal R. Grzadkowski, Hannah D. Holly, Julia Somers, Emek Demir
The paper systematically examines mutation groupings in cancer genes to identify downstream expression programs and reveals functional divergence among mutations within the same gene.
Christine P’ng, Jeffrey J. Green, Lauren C. Chong…·Paul Christopher Boutros
BPG is an R package that generates publication-quality, customizable plots and offers an interactive web tool for figure customization and integration with computational pipelines.
Syed Aleem Haider, Cindy Q. Yao, Vicky S. Sabine…·Paul Christopher Boutros
The paper introduces SIMMS, a method that identifies biomarkers by analyzing molecular data and biological networks, showing improved performance in predicting disease subtypes and outcomes.
Michal R. Grzadkowski, Syed Aleem Haider, Dorota H.S. Sendorek, Paul Christopher Boutros
The paper compares gene-based and subnetwork-based biomarkers in breast cancer, finding subnetwork biomarkers more robust and performant across different patient cohorts.