Sherihan Samir

This study identifies CdgR as a c-di-GMP receptor in Synechocystis that regulates type IV pilus-dependent functions through interactions with transcription factors SyCRP1 and SyCRP2.

The paper identifies ComFB as a new family of c-di-NMP receptors in bacteria, showing they bind c-di-GMP and c-di-AMP and regulate cellular processes like motility.

The paper shows that c-di-AMP regulates natural competence in cyanobacteria via the ComFB signaling protein, which is essential for pilus biogenesis and DNA uptake.

The paper shows ComFB binds c-di-GMP to inhibit motility in B. subtilis by affecting flagellar activity, independent of MotI.