Cell BiologybioRxivPreprint
Development of Long-Term Human Adipocyte Organoids Manifesting Aging in Response to Intermittent Hypoxia
Yunzhou Dong, Jingjing Wang, Feifei Feng…·Virend Kristen Somers
This paper develops a long-term human adipocyte organoid system that models IH-induced aging and dysfunction, showing reduced adipogenesis, structural abnormalities, and impaired insulin signaling.