Author

Rosa de Groot

Leiden University Medical CenterORCID 0000-0003-4070-0848Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Approach:statistical model· 1

Frequent Co-Authors

Monika C. WolkersiD· 2 shared Suzanne M. CastenmilleriD· 2 shared Alexander A. F. A. Veenhof· 1 shared Alida F. W. van der SteegiD· 1 shared Anne L. BorstiD· 1 shared Aurélie GuislainiD· 1 shared Benoît P. NicoletiD· 1 shared David VermijleniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Monika C. WolkersORCID

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2 papers

Recent·Most cited

Cancer BiologyLife Science AlliancePeer-reviewedAug 22, 2025

γδ T cells are the prime anti-tumoral T cells in pediatric neuroblastoma

Suzanne M. Castenmiller, Anne L. Borst, Leyma Wardak…·Monika C. Wolkers

The paper shows that γδ T cells, not β T cells, are the main anti-tumoral immune cells in pediatric neuroblastoma after chemotherapy.

8 citationstop 4%

humanbulk RNA-seq

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ImmunologyOncoImmunologyPeer-reviewedAug 22, 2024

Tertiary lymphoid structure-related immune infiltrates in NSCLC tumor lesions correlate with low tumor-reactivity of TIL products

Suzanne M. Castenmiller, Nandhini Kanagasabesan, Aurélie Guislain…·Monika C. Wolkers

This study identifies that high B cell infiltrates in NSCLC tumors, associated with tertiary lymphoid structures, negatively correlate with the tumor-reactivity of expanded TIL products.

9 citations

humanflow cytometry

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