Benjamin G Faber

TRIDENT is a framework for robust multi-trait GWAS that identifies 66 novel osteoarthritis signals by combining earlier and larger GWAS meta-analyses and applying translational annotation.

This study identifies 20 genetic loci associated with knee alignment and shows genetic correlation with knee osteoarthritis, suggesting osteoarthritis may causally influence alignment.

This study identifies four genetic loci associated with hip morphology in Chinese populations through GWAS, with two loci previously linked to musculoskeletal development and two being novel findings.

This study identifies genetic determinants of hip joint space width and finds they have opposing causal effects on hip osteoarthritis risk through distinct mechanisms.