Sijia Wang

This study analyzes methylome and transcriptome data from stressed and relaxed individuals to show psychological stress affects skin via epigenetic changes and gene expression, particularly in glutamatergic synapse pathways.

This paper evaluates polygenic and methylation risk scores for predicting overweight-related hypertension in Chinese populations, finding improved accuracy with integrated multi-omics approaches.

This study introduces LEAP, a method for estimating shared proteomic architectures across traits, finding 585 significant proteomic correlations among 50 traits using UK Biobank data.

The paper identifies novel structural variants in Han Chinese genomes using long-read sequencing and links them to phenotypic diversity and disease susceptibility.

This paper introduces a deep learning model called Nailnet for segmenting fingernail plate and lunula from hand images, achieving high IoU and accuracy scores.

Genomics-FM is a foundation model that reduces reliance on labeled data and outperforms existing models in genome annotation, epigenomic prediction, and variant effect assessment.

This study identifies four genetic loci associated with hip morphology in Chinese populations through GWAS, with two loci previously linked to musculoskeletal development and two being novel findings.

This study identifies genetic associations between olfactory receptors and odor perception in humans, revealing novel links and supporting the hypothesis of olfactory gene degradation.

FastQTLmapping is a C++ package that performs mQTL analysis and large-scale linear regressions efficiently, outperforming MatrixEQTL in speed and memory usage.

This study identifies five novel genetic loci associated with facial morphology traits in Han Chinese through a genome-wide association analysis of 3D facial data.

This study identifies 24 genetic loci associated with facial shape variation in humans through GWAS and confirms 13 of them in a multi-ethnic cohort.

The paper identifies six genome-wide significant loci associated with facial shape differences between Europeans and Han Chinese and develops a DNA-based 3D face prediction model.