Olin Silander

This study identifies a gene-distal polygenic architecture underlying a dominant axis of human trait covariation, showing structured cross-trait information in the sub-significant polygenic background.

This paper benchmarks RNA modification detection tools on bacterial rRNA using Oxford Nanopore DRS, finding that no single tool recovers all sites and that combining tools improves performance.

This paper presents a high-quality genome assembly of the hourglass dolphin using Oxford Nanopore sequencing, achieving high contiguity and completeness for marine mammal genomics.

pyRforest integrates Python's Random Forest algorithms into R for efficient genomic data classification and analysis, offering improved interpretability and additional statistical methods.

The paper identifies immune-related gene and microbial biomarkers associated with complete response to chemoradiotherapy in rectal cancer.

The paper reports an atypical mitochondrial genome structure in the marine isopod Isocladus armatus using long-read sequencing, revealing two mitochondrial chromosomes with unique configurations.

This study benchmarks hybrid bacterial genome assembly methods using Illumina and Oxford Nanopore data from 49 E. coli isolates, finding method-specific advantages in structural and sequence accuracy.

This study shows that the synthetic RiboJ ribozyme maintains high splicing efficiency across diverse E. coli genetic backgrounds and is robust to cis- and trans-genetic changes.

Bac-PULCE enables rapid bacterial strain and AMR profiling using CRISPR-based enrichment and long-read sequencing with minimal infrastructure.

This study compares short- and long-read metagenomics for bacterial and eukaryotic community classification, finding that long reads improve accuracy, especially for non-microbial communities.

This paper introduces a method for rapid and inexpensive whole-genome sequencing of SARS-CoV-2 using tiled amplicons and Oxford Nanopore Rapid Barcoding, achieving high-quality results with fewer reads.