ImmunologyNaturePeer-reviewed
Prdm16-dependent antigen-presenting cells induce tolerance to intestinal antigens
Liuhui Fu, Rabi Upadhyay, Maria V. Pokrovskii…·Dan R. Littman
This study identifies Prdm16-dependent tolerogenic dendritic cells (tDC) that induce regulatory T cells to promote oral tolerance to food and microbiota antigens in mice and humans.