Author

Francis M. Chen

New York UniversityORCID 0000-0002-6615-4155Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Dan R. LittmaniD· 2 shared Gabriela Romero‐MezaiD· 2 shared Rabi UpadhyayiD· 2 shared Adam GriesemeriD· 1 shared E. A. Schulman· 1 shared Elizabeth S. SattelyiD· 1 shared Jamie BlumiD· 1 shared Kazuki NagashimaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Dan R. LittmanORCID

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2 papers

Recent·Most cited

Identification and characterization of dietary antigens in oral tolerance

Jamie Blum, Ryan Kong, E. A. Schulman, Francis M. Chen, Rabi Upadhyay, Gabriela Romero‐Meza, Dan R. Littman, Michael Andrew Fischbach, Kazuki Nagashima, Elizabeth S. Sattely

The paper identifies seed storage protein epitopes as targets of intestinal regulatory T cells that modulate immune responses to dietary antigens.

Science Immunology · Mar 6, 2026Peer-reviewedImmunology

Prdm16-dependent antigen-presenting cells induce tolerance to intestinal antigens

Liuhui Fu, Rabi Upadhyay, Maria V. Pokrovskii, Francis M. Chen, Gabriela Romero‐Meza, Adam Griesemer, Dan R. Littman

This study identifies Prdm16-dependent tolerogenic dendritic cells (tDC) that induce regulatory T cells to promote oral tolerance to food and microbiota antigens in mice and humans.

Nature · Apr 14, 2025Peer-reviewedImmunology