ImmunologyPLoS PathogensPeer-reviewed
CD4+ but not CD8+ T cells are required for protection against severe guinea pig cytomegalovirus infections
Tyler B. Rollman, Zachary W. Berkebile, Dustin Hicks…·Craig J. Bierle
This study shows CD4+ T cells are critical for preventing severe congenital cytomegalovirus infection in guinea pigs, while CD8+ T cell depletion increases placental viral load without affecting disease severity.