Author

Mark R. Schleiss

University of MinnesotaORCID 0000-0002-2108-9433Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Craig J. BierleiD· 2 shared Mark Blackstad· 2 shared Adam P. GeballeiD· 1 shared Alexey J Badillo-Guzman· 1 shared Cheryl A. GaleiD· 1 shared Christine E Tanna· 1 shared Claudia Fernández-AlarcóniD· 1 shared Dan KnightsiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

Craig J. BierleORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Replication-Deficient Whole-Virus Vaccines Against Cytomegalovirus Induce Protective Immunity in a Guinea Pig Congenital Infection Model

Mark R. Schleiss, Claudia Fernández-Alarcón, Craig J. Bierle, Adam P. Geballe, Alexey J Badillo-Guzman, Christine E Tanna, Kanokpan Tsriwong, Mark Blackstad, Jian Ben Wang, Michael A. McVoy

This study evaluates two replication-deficient whole-virus vaccines against GPCMV in a guinea pig model, showing they are attenuated and provide protective immunity against maternal viremia and congenital infection.

Journal of Virology · Jun 11, 2025Peer-reviewedImmunology

CD4+ but not CD8+ T cells are required for protection against severe guinea pig cytomegalovirus infections

Tyler B. Rollman, Zachary W. Berkebile, Dustin Hicks, Jason S. Hatfield, Priyanka Chauhan, Marco Pravetoni, Mark R. Schleiss, Gregg N. Milligan, Terry K. Morgan, Craig J. Bierle

This study shows CD4+ T cells are critical for preventing severe congenital cytomegalovirus infection in guinea pigs, while CD8+ T cell depletion increases placental viral load without affecting disease severity.

PLoS Pathogens · Nov 4, 2024Peer-reviewedImmunology

Human Cytomegalovirus in breast milk is associated with milk composition, the infant gut microbiome, and infant growth

Kelsey E. Johnson, Nelmary Hernandez-Alvarado, Mark Blackstad, Timothy J. Heisel, Mattea Allert, David A. Fields, ELVIRA M. ISGANAITIS, Katherine M. Jacobs, Dan Knights, Eric F. Lock, Michael C. Rudolph, Cheryl A. Gale, Mark R. Schleiss, Frank Wolfgang Albert, Ellen W. Demerath, Ran Blekhman

The paper investigates the association between human cytomegalovirus in breast milk and milk composition, infant gut microbiome, and infant growth.

Nature Communications · Jul 23, 2024Peer-reviewedGenomics