Cell BiologyThe EMBO JournalPeer-reviewed
Locally released somatostatin triggers cAMP and Ca2+ signaling in primary cilia to modulate pancreatic β-cell function
Ceren Incedal Nilsson, Özge Dumral, Gonzalo Sanchez…·Olof Idevall‐Hagren
This study shows that somatostatin acting on primary cilia of pancreatic β-cells modulates cAMP and Ca2+ signaling, affecting β-cell function and linking cilia length to type-2 diabetes.