Author

Lukas Adam

Berlin Institute of Health at Charité - Universitätsmedizin BerlinORCID 0000-0003-4182-5300Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Roland EilsiD· 2 shared Chiara Di Ponzio· 1 shared Christian ConradiD· 1 shared Dominik NiopekiD· 1 shared Fabian SpringeriD· 1 shared Foo Wei TeniD· 1 shared Jan MathonyiD· 1 shared Maik Brune· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersSystems Biology

Roland EilsORCID

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2 papers

Recent·Most cited

Systems BiologyScience SignalingPeer-reviewedSep 26, 2023

Dynamics of SARS-CoV-2 host cell interactions inferred from transcriptome analyses

Lukas Adam, Megan Lynn Stanifer, Fabian Springer…·Stefan M. Kallenberger

This study uses time-resolved RNA sequencing and mathematical modeling to analyze SARS-CoV-2 host cell interactions, revealing transcriptional dynamics and identifying druggable host pathways.

7 citations

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsNature Machine IntelligencePeer-reviewedDec 7, 2020

Gene set inference from single-cell sequencing data using a hybrid of matrix factorization and variational autoencoders

Soeren Lukassen, Foo Wei Ten, Lukas Adam…·Christian Conrad

The paper introduces a hybrid model combining matrix factorization and variational autoencoders to infer gene sets from scRNA-seq data, correcting batch effects and identifying cell types.

8 citations

scRNA-seqmatrix factorization

𝕏 PostBluesky