Author

Yue Guo

State Key Laboratory of Pharmaceutical BiotechnologyORCID 0000-0003-4191-3183Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yue Guo2 papers · Nanjing Agricultural University

Biology Disciplines

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Genetic & Genomic Medicine· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:contrastive learning· 1

Frequent Co-Authors

Jingping YangiD· 3 shared Kangchun Wang· 2 shared Luyu Gong· 2 shared Qiaoqiao LiuiD· 2 shared Bolei Zhang· 1 shared Changming ZhangiD· 1 shared Erguang LiiD· 1 shared Jing Zhang· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Jingping YangORCID

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3 papers

Recent·Most cited

In vivo measurement and prediction of cell-type-resolved non-coding variant effects in human immunity

Qiaoqiao Liu, Jingjing Zhang, 诸叶平, Kangchun Wang, Changming Zhang, Ying Jin, Yang Zhang, Zhaojun Liu, Yue Guo, Jingping Yang, Zhihong Liu

The paper measures and predicts non-coding variant effects in human immune cells using single-cell ATAC-seq and whole-genome sequencing, revealing regulatory mechanisms and applications in systemic lupus erythematosus.

medRxiv · May 6, 2026 · PreprintGenetic & Genomic Medicine

Unlocking cross-modal interplay of single-cell and spatial joint profiling with CellMATE

Qi Wang, Bolei Zhang, Luyu Gong, Yue Guo, Erguang Li, Jingping Yang

CellMATE is a method that captures both additive and synergistic benefits of multimodal joint profiling by integrating single-cell and spatial data into a unified latent space.

bioRxiv · Sep 6, 2024 · PreprintBioinformatics

Locus-specific stratification and prioritization unveil high risk genes underlying hyperuricemia

Jing Zhang, Yue Guo, Luyu Gong, Limei Xia, Qiaoqiao Liu, Kangchun Wang, Qi Wang, Zhaojun Liu, Zhaohui Steve Qin, Shaolin Shi, Jingping Yang

This study introduces a method to identify causal genes and regulatory mechanisms in hyperuricemia by integrating single-cell data with genetic findings.

medRxiv · Mar 6, 2024 · PreprintGenetic & Genomic Medicine