Camille M. Hanes

The paper describes a mouse mutant lacking the Pcdhgc5 isoform, finding no major disruption in cerebral cortex development despite changes in synaptic-related pathways.

The paper investigates the role of specific Pcdhg isoforms in neuronal self-avoidance and survival in mouse starburst amacrine cells, finding that {gamma}C4 is essential for survival but not self-avoidance.

This study shows that phosphorylation of a shared C-terminal motif in γ-Protocadherin negatively regulates dendrite arborization in cortical neurons, with a C-terminal deletion causing the strongest phenotype.