Andrew M. Garrett

The paper describes a mouse mutant lacking the Pcdhgc5 isoform, finding no major disruption in cerebral cortex development despite changes in synaptic-related pathways.

The paper investigates the role of specific Pcdhg isoforms in neuronal self-avoidance and survival in mouse starburst amacrine cells, finding that {gamma}C4 is essential for survival but not self-avoidance.

The paper characterizes mouse retinal ganglion cell types labeled by two AAV vectors, finding they label distinct subsets and axonal populations beyond expected from promoter expression.

This study shows that phosphorylation of a shared C-terminal motif in γ-Protocadherin negatively regulates dendrite arborization in cortical neurons, with a C-terminal deletion causing the strongest phenotype.

This study shows that γ-protocadherin isoforms are critical for synapse formation and peripheral branching in touch sensory neurons, and their loss disrupts corticospinal synapses.

The paper uses CRISPR/Cas9 to disrupt isoforms of the Pcdhg gene cluster in mice, finding that Pcdhgc4 is the only critical isoform for neuronal function.