Vishnu Muraleedharan Saraswathy

This study identifies elevated phagocytic capacity as essential for innate spinal cord repair by comparing zebrafish and mammalian immune responses.

This study identifies Hapln1-HA signaling as a pro-regenerative mechanism in zebrafish spinal cord injury by enhancing progenitor cell proliferation and repair.

This study identifies sox2+ progenitors as critical for zebrafish spinal cord regeneration and shows Bach1 transcription factors regulate their activation and quiescence.

The paper shows that systemic muscle injury in zebrafish activates Hb-EGF in the epidermis, which is necessary for systemic repair, while local injury does not require Hb-EGF.

This study uses single nuclear RNA sequencing to analyze spinal cord regeneration in zebrafish, identifying neurogenesis and plasticity as key mechanisms for recovery.

This study shows that Mib1, a Notch signaling regulator, is also essential for Planar Cell Polarity (PCP) through RhoA-dependent mechanisms and Ryk endocytosis.

This study shows myostatin b inhibits neurogenesis in zebrafish spinal cord, and its loss improves functional recovery without affecting axonal or glial bridging.

This study shows that Delta/Notch signaling is essential for spinal cord morphogenesis in zebrafish by regulating neuroepithelial polarity and division behavior.