Yuxiao Xu

Hapln1-HA signaling promotes progenitor cell proliferation and spinal cord regeneration

This study identifies Hapln1-HA signaling as a pro-regenerative mechanism in zebrafish spinal cord injury by enhancing progenitor cell proliferation and repair.

Transient activation of potent progenitor cells is required for spinal cord regeneration

This study identifies sox2+ progenitors as critical for zebrafish spinal cord regeneration and shows Bach1 transcription factors regulate their activation and quiescence.

Spinal cord regeneration deploys adult molecular programs that do not recapitulate embryonic development

The paper examines whether spinal cord regeneration in adult zebrafish recapitulates embryonic development by analyzing single-cell RNA-seq data across development, homeostasis, and regeneration.

Pleiotropy of autism-associated chromatin regulators

The paper investigates the role of chromatin regulators in autism spectrum disorder (ASD) by examining their involvement in microtubule biology and cellular proliferation, finding that ASD risk genes affect these processes and are enriched among microtubule-associated proteins.

The atypical RNA-binding protein TAF15 regulates dorsoanterior neural development through diverse mechanisms in Xenopus tropicalis.

This study identifies TAF15's role in dorsoanterior neural development in Xenopus tropicalis through two distinct regulatory mechanisms affecting fgfr4 and ventx2.1.

DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract

The paper investigates congenital kidney and urinary tract anomalies and genital defects in DYRK1A mutation carriers, showing DYRK1A's role in genitourinary development through Xenopus studies.