Qiwei Ye

The paper introduces RiboGRAM, a model that learns non-coding RNA sequence grammar for structural and regulatory inference across multiple organisms.

This study reports cryo-EM structures of GGCX bound to VKDPs and vitamin K, revealing its dual-catalytic mechanism and disease-associated mutation clusters.

This paper introduces OC2, a generative model that samples biomolecular conformational ensembles efficiently, demonstrating accuracy in reproducing experimental data and capturing dynamic biological processes.

OpenComplex predicts 3D atomic-level structures of biomolecular complexes using models based on AlphaFold2 and AlphaFold-Multimer, achieving accuracy comparable to or better than existing methods.

This paper introduces LEGO, a self-supervised learning method for 3D molecular structures using tetrahedrons as building blocks, showing improved performance in molecular property prediction.