Simon G. Coetzee

This study identifies M2 macrophages and IL1 signaling as key mediators of endometriosis risk and shows their pleiotropic role in comorbid traits.

This study shows that DNA methylation and gene expression patterns are preserved in recurrent high grade serous ovarian cancers, with BRCA1/2 carriers showing more shared methylation changes and improved survival.

ELMER v.2 reconstructs gene regulatory networks from DNA methylation and transcriptome data to identify Master Regulators in diseases like breast cancer.

HiCAGE provides an R package for annotating and visualizing 3C-based genomic data, integrating with RNA-seq and gene ontologies.

The paper introduces StateHub and StatePaintR to provide rapid, reproducible chromatin state annotations for genome annotation, supporting variant prioritization and analysis.