Shaji K. Chacko

The study shows that enteral OCA prevents cholestasis and intestinal atrophy in neonatal pigs by enhancing bile acid and sterol transport through FXR target genes, with additional intestinal growth benefits.

The paper develops and validates a high-throughput UHPLC-MS/MS method to quantify 39 spinach flavonoids, showing comparable results to traditional methods and providing first quantitative reports for many compounds.

This study shows that chronic beta3-AR stimulation improves metabolic function in aged mice by enhancing thermogenesis in brown adipose tissue and lipid turnover in white adipose tissue.