Cezar Gavrilovici

This study shows that SCN1A haploinsufficiency disrupts neural progenitor networks and accelerates neurogenesis in human Dravet syndrome forebrain assembloids, leading to altered corticogenesis and circuit hyperexcitability.

This study shows that loss-of-function mutations in zebrafish slc13a5 cause epilepsy-like phenotypes, which are rescued by blocking NMDA receptor signaling.

This paper uses zebrafish kcna1a-/- mutants to model EA1 and epilepsy, showing ataxia-like behaviors, brain hyperexcitability, and responsiveness to carbamazepine.