Kirsten H. Limesand

This study examines immune cell dynamics in mouse parotid glands after radiation therapy, finding dysregulated immune responses that may contribute to chronic dysfunction.

This study investigates radiation-induced changes in energy metabolism in salivary glands, finding altered glycolytic and oxidative phosphorylation rates and mitochondrial dysfunction over time.

This study shows that AMPK activators like AICAR and metformin reverse radiation-induced salivary gland dysfunction by restoring cell polarity and differentiation markers.

The paper uses scRNA-seq to analyze chronic irradiation effects on mouse parotid glands, identifying Etv1+ epithelial cells and transcriptional changes in immune and secretory cells.