Haotian Guo

This paper introduces PandaPure, a synthetic organelle-based method for protein purification that simplifies and enhances the process in Escherichia coli.

The paper designs universal riboregulators using deep learning to predict RNA sequences that suppress CRISPR-Csy4-mediated pre-crRNA processing.

This paper introduces TEARS, synthetic microdomains in E. coli that enable spatial control of biochemical processes through phase-separated RNA structures.

The paper introduces Seq2DFunc, a 2D CNN for predicting nucleic acid sequence functions from synthetic data, showing improved performance over 1D CNNs with smaller datasets.