Nipam H. Patel

This study shows that lepidopteran scale cells originate from sensory organ precursors through a canonical lineage, supported by live imaging and single-nucleus RNA sequencing.

The paper investigates the genetic basis of limb diversity in arthropods by analyzing gene expression and CRISPR-Cas9 phenotypes in crustaceans.

The paper identifies a novel expression domain of extradenticle in harvestman patella, suggesting that modification of an ancient gene, not neofunctionalization of a new copy, underlies the origin of the chelicerate patella.

The paper investigates the function of Hox genes lab and Dfd in chelicerates, showing their role in head segment patterning and homeotic transformations through RNAi experiments and expression analysis.

The paper investigates whether the Daphnia carapace is a novel structure by comparing gene expression patterns across species and concludes it is homologous to ancestral structures.

This paper identifies and classifies cis-regulatory elements in Parhyale hawaiensis using Omni-ATAC-Seq and RNA-Seq, revealing dynamic regulatory features during embryonic development.

This study identifies Polycomb Group proteins in crustaceans and shows they regulate Hox genes differently than in insects, revealing distinct regulatory mechanisms in body plan evolution.

The paper investigates Hox gene cross-regulatory interactions in Parhyale hawaiensis, revealing combinatorial Hox gene function rather than posterior prevalence in specifying appendage identity.

The paper uses gene expression analysis in tarantulas to determine the evolutionary origins of arthropod ectodermal structures, finding they derive from ancestral leg bases.

CRISPR-Cas9 knockout of leg gap genes in a crustacean reveals that insect wings are not novel structures, they evolved from crustacean leg segments.

The paper investigates the developmental and structural basis of wing transparency in the glasswing butterfly Greta oto, identifying reduced scale precursor cell density and wax-based nanopillars as key features.

The paper sequences and annotates the genome of Parhyale hawaiensis, identifying key genes for development, immunity, and lignocellulose digestion, providing a resource for comparative studies.