The molecular basis of arthropod appendage diversity
Heather Suzanne Bruce, Nipam H. Patel
The paper investigates the genetic basis of limb diversity in arthropods by analyzing gene expression and CRISPR-Cas9 phenotypes in crustaceans.
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Marine Biological LaboratoryORCID 0000-0003-3199-8224Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
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Heather Suzanne Bruce, Nipam H. Patel
The paper investigates the genetic basis of limb diversity in arthropods by analyzing gene expression and CRISPR-Cas9 phenotypes in crustaceans.
Guilherme Gainett, Benjamin C. Klementz, Pola O. Blaszczyk…·Prashant P. Sharma
The paper investigates the function of Hox genes lab and Dfd in chelicerates, showing their role in head segment patterning and homeotic transformations through RNAi experiments and expression analysis.
Heather Suzanne Bruce, Nipam H. Patel
The paper investigates whether the Daphnia carapace is a novel structure by comparing gene expression patterns across species and concludes it is homologous to ancestral structures.
Dennis August Sun, Jessen V. Bredeson, Heather Suzanne Bruce, Nipam H. Patel
This paper identifies and classifies cis-regulatory elements in Parhyale hawaiensis using Omni-ATAC-Seq and RNA-Seq, revealing dynamic regulatory features during embryonic development.
Heather Suzanne Bruce, Nipam H. Patel
The paper uses gene expression analysis in tarantulas to determine the evolutionary origins of arthropod ectodermal structures, finding they derive from ancestral leg bases.
Heather Suzanne Bruce, Nipam H. Patel
CRISPR-Cas9 knockout of leg gap genes in a crustacean reveals that insect wings are not novel structures, they evolved from crustacean leg segments.
Damian Kao, Alvina Grace Lai, Evangelia Stamataki…·Aziz A. Aboobaker
The paper sequences and annotates the genome of Parhyale hawaiensis, identifying key genes for development, immunity, and lignocellulose digestion, providing a resource for comparative studies.