Author

Sarah C. Linn

Nationwide Children's HospitalORCID 0000-0003-4337-2966Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron A. SimoniiD· 1 shared Alejandro LIanes· 1 shared Ashley R. JacksoniD· 1 shared Bryanna Nicole FayneiD· 1 shared Israel Cotzomi-OrtegaiD· 1 shared John David SpenceriD· 1 shared Juan de Dios Ruiz‐RosadoiD· 1 shared Kalvis BrangulisiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Aaron A. SimoniORCID

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2 papers

Recent·Most cited

Cell BiologyiSciencePeer-reviewedOct 25, 2025

Obesity promotes urinary tract infection by disrupting urothelial immune defenses

Laura Schwartz, Kristin Salamon, Aaron A. Simoni…·John David Spencer

This study shows obesity increases UTI risk by altering bladder immune defenses through focal adhesion kinase activation in mice and human cells.

4 citations

mousebulk RNA-seq

𝕏 PostBluesky

MicrobiologyPLoS neglected tropical diseasesPeer-reviewedSep 23, 2024

Enhancement of clinical signs in C3H/HeJ mice vaccinated with a highly immunogenic Leptospira methyl-accepting chemotaxis protein following challenge

Liana Nunes Barbosa, Alejandro LIanes, Swetha Madesh…·Sreekumari Rajeev

This study evaluates a recombinant Leptospira methyl-accepting chemotaxis protein (MCP) vaccine in C3H/HeJ mice, finding it elicits an immune response but does not prevent disease and may exacerbate clinical signs.

1 citation

mouseproteomics

𝕏 PostBluesky