Tanvi Butola

This study corrects a pathogenic SERPINI1 mutation in iPSC-derived neurons using a personalized base editor to treat FENIB and related neurodegenerative diseases.

The paper introduces ClearScope, a fully integrated light sheet theta microscope for sub-cellular resolution imaging of large specimens without lateral size constraints, demonstrating its use on mouse and human brain samples.

This paper investigates the role of RIM-BP2 in organizing Ca2+ channel topography and regulating synaptic vesicle release probability and replenishment at a fast central synapse.