Jayeeta Basu

This study identifies purinergic signaling via P2RY1 receptors and nuclear calcium transients as a driver of glioblastoma tumorigenesis, with therapeutic potential through P2RY1 inhibition.

This study shows that high-demand tasks increase hippocampal place cell stability, which is partially supported by the lateral entorhinal cortex.

The paper investigates bidirectional interactions between hippocampal sharp wave ripples and neocortical slow oscillations during sleep using electrophysiology and imaging in mice.

This study corrects a pathogenic SERPINI1 mutation in iPSC-derived neurons using a personalized base editor to treat FENIB and related neurodegenerative diseases.

The paper introduces ClearScope, a fully integrated light sheet theta microscope for sub-cellular resolution imaging of large specimens without lateral size constraints, demonstrating its use on mouse and human brain samples.

This study identifies how glutamatergic and GABAergic projections from the entorhinal cortex bidirectionally control pattern separation and completion in the hippocampus, influencing context discrimination and generalization.

This study shows that LEC inputs drive dendritic spikes in CA1 pyramidal neurons via a disinhibitory VIP interneuron circuit, revealing a mechanism for context-specific hippocampal coding.

This study investigates how hippocampal place cell maps remain stable during memory recall in mice, showing increased stabilization after memory consolidation.

Hippocampal pyramidal cells show branch-specific tuning for different place fields, and their coupling to their soma changes with experience of an environment.