Matthew Isada

This study uses ribosome profiling to analyze translational dynamics between an archaeal virus and its host, revealing co-regulated gene expression and post-transcriptional regulation during infection.

The paper estimates rates of meiotic and mitotic errors in human embryos using simulation and approximate Bayesian computation, finding high levels of chromosomal mosaicism.

This paper develops an optimized protocol for producing and benchmarking MNaseA and MNaseB, showing MNaseA's superior activity in high-salt conditions for ribosome profiling in halophilic archaea.