Author

Jaime A. Espina

Physics of LifeORCID 0000-0003-4357-7179Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Elías H. BarrigaiD· 3 shared Artemis G. KorovesiiD· 2 shared Ana Patricia RamosiD· 1 shared Anna ErzbergeriD· 1 shared Caren NordeniD· 1 shared Fernando FerreiraiD· 1 shared Ian S. MazeiD· 1 shared Inês FerreiraiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersDevelopmental Biology

Elías H. BarrigaORCID

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3 papers

Recent·Most cited

Mechanical control of histone serotonylation initiates neural crest migration in vivo

Joana E. Saraiva, Artemis G. Korovesi, Xiaoran Wei, Jaime A. Espina, Miguel Almeida Ribeiro, Ian S. Maze, Elías H. Barriga

The paper shows that histone serotonylation, induced by mesoderm stiffening through Tgm2 nuclear translocation, is essential for initiating collective neural crest cell migration in vivo.

bioRxiv · Oct 21, 2025 · PreprintDevelopmental Biology

Piezo1-Yap1 signalling translates tissue mechanics into regenerative cell states.

Fernando Ferreira, Jaime A. Espina, Artemis G. Korovesi, Inês Ferreira, Quentin Tirel, Elías H. Barriga

This study identifies a mechanical signal, Piezo1-Yap1, that coordinates cell state transitions during regeneration by translating tissue stiffness into regenerative competence.

bioRxiv · Sep 20, 2025 · PreprintDevelopmental Biology

Nuclear deformability facilitates apical nuclear migration in the developing zebrafish retina

Mariana Maia-Gil, Maria Gorjão, Roman Belousov, Jaime A. Espina, João Coelho, Juliette Gouhier, Ana Patricia Ramos, Elías H. Barriga, Anna Erzberger, Caren Norden

This study shows that increased Lamin A expression reduces nuclear deformability and impairs apical nuclear migration in zebrafish retinal neuroepithelium.

Current Biology · Oct 31, 2024Peer-reviewedDevelopmental Biology