Caren Norden

The paper shows that shared neurogenesis onset explains bilateral symmetry in zebrafish retinas through experiments and a stochastic model.

The paper shows that neuronal migration in the vertebrate retina switches from active, microtubule-dependent translocation to passive, tissue-driven displacement depending on the tissue lamination state.

The paper shows that neurogenic progenitors in zebrafish retinas can undergo self-renewal to compensate for apoptosis, ensuring proper development despite cell loss.

The paper investigates how apical forces drive optic cup invagination during vertebrate eye development through coordinated cell behaviors and physical modeling.

The paper investigates how guidance cues coordinate multipolar migration in developing retinal neurons, revealing repulsive and attractive signaling pathways that guide proper lamination.

The paper shows that nuclear shape changes and packing order during neurogenesis are critical for retinal lamination in zebrafish.

This study shows that increased Lamin A expression reduces nuclear deformability and impairs apical nuclear migration in zebrafish retinal neuroepithelium.

The paper uses live imaging to show that retinal progenitors make both deterministic and probabilistic fate decisions, with stochasticity increasing under developmental stress.

The paper shows that horizontal cells in the zebrafish retina use amoeboid-like migration to navigate crowded tissue and form the correct layer.

The paper shows that extracellular matrix topology influences collective cell migration during zebrafish optic cup formation by affecting cryptopodia formation and migration efficiency.

The paper shows mechanical forces reduce endocardial cell volume during zebrafish cardiac valve formation through TRPP2/TRPV4 channels and hyaluronic acid.

The paper shows bidirectional neuronal migration prevents spatial competition during retinal morphogenesis in zebrafish, human tissue, and organoids.

The paper shows that Notch regulates asymmetric neurogenic commitment in zebrafish retinal progenitors through Sara-positive endosomes, revealing a new mechanism for progenitor differentiation.

The paper shows that Yap/Taz-TEAD activity mediates mechanical signal sensing in hindbrain boundary cells, linking mechanical cues to progenitor behavior and cell fate changes.

The paper shows that stochastic single cell behavior in zebrafish retina leads to robust horizontal cell layer formation despite heterogeneity in cell dynamics.

This paper shows that overexpressing Klf4 in retinal progenitor cells can reprogram them to generate retinal ganglion cells in vivo, with iRGCs surviving for up to 30 days.

This paper demonstrates how deep learning-based image restoration extends fluorescence microscopy's capabilities by improving resolution, reducing photon exposure, and increasing frame rates.

The paper shows that non-cell autonomous actin redistribution drives isotropic growth of the zebrafish retinal neuroepithelium by increasing cell height.

This study identifies the coordinated cellular mechanisms of basal shrinkage and epithelial migration in zebrafish retinal neuroepithelium formation and their role in optic cup development.

This study shows that ganglion cells in zebrafish use two distinct translocation modes to correctly form the retinal layer, with failure leading to lamination defects.