Xiaoran Wei

This study identifies QR2 as a reader of H3Q5ser, showing its role in human neuron development through transcriptional and electrophysiological effects.

The paper shows that histone serotonylation, induced by mesoderm stiffening through Tgm2 nuclear translocation, is essential for initiating collective neural crest cell migration in vivo.

This study shows that mild brain injury increases dopaminergic neurodegeneration and Lewy body pathology in mice, and that reducing T cell infiltration improves outcomes.

The paper maps 5mC and 5hmC modifications in mouse cortical cell types using Nanopore sequencing and RNA sequencing, revealing astrocytes as a major source of 5hmC and providing a resource for methylome analysis.