D. Annie Doyle

This study shows that enterobactin synthesis and uptake are essential for multi-drug resistant Klebsiella pneumoniae to grow under zinc limitation, independent of iron and Zur regulation.

This paper identifies a 'self-gapping' mechanism in bacterial COG0523 metallochaperones where the C-terminal domain activates GTP hydrolysis via an arginine finger and lysine residue, revealing a novel regulatory mechanism.