Scott Wolf

This study uses longitudinal sequencing in Drosophila to show that genomic response to selection involves both polygenic shifts and epistatic interactions, with DEGs enriched for selected SNPs.

The paper shows that in queenless bumble bee colonies, workers show increased behavioral variation and take on influential roles, leading to a shift from centralized to decentralized social networks.

pipemake creates modular Snakemake workflows for reproducible biological data analysis, reducing hands-on time and enabling flexible pipeline adaptation.

The paper analyzes gene expression variance across 57 RNA-seq datasets to show that transcriptional variance is consistent across tissues and linked to gene function, sequence variation, and regulatory features.

The paper maps eQTLs in Drosophila melanogaster using an outbred panel, identifying cis and trans regulatory loci for most expressed genes and revealing non-modular gene co-expression networks.

This paper introduces a low-cost method to validate SNP-level genetic effects in outbred populations, demonstrating its utility in Drosophila for longevity traits.