ImmunologyAmerican Journal of Respiratory Cell and Molecular BiologyPeer-reviewed
Dysregulated airway epithelial antiviral immunity in Down Syndrome impairs type III IFN response and amplifies airway inflammation during RSV infection.
Elizabeth A. Chorvinsky, Surajit Bhattacharya, Betelehem Solomon Bera…·Gustavo Niño
This study shows that Down Syndrome impairs type III IFN response and increases proinflammatory mediators in airway epithelial cells during RSV infection, leading to severe inflammation.
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