Meredith E. Jackrel

This study examines how substituents on benzyl groups affect self-assembly and immunogenicity of amphipathic peptides, showing that chemical modifications influence fibril formation and immune responses.

The paper develops human tri-lineage brain microtissues composed of neurons, astrocytes, and microglia, showing they recapitulate cell-cell interactions and pathological processes.

This paper shows that enantiomeric histidine-rich peptides form coacervates that enhance antigen delivery to T cells, improving immune response.

This study shows that TDP-43 aggregate seeds persist in both mouse and human skeletal muscle even after the removal of large TDP-43 inclusions.