Substituent-based Modulation of Self-Assembly and Immunogenicity of Amphipathic Peptides
Anirban Das, Ushasi Pramanik, Elise M. Brown, Chih-Yun Liu, Huan Gong, Jonathan L. Fascetti, Mark Gibson, Samuel T. Stealey, Silviya P. Zustiak, Cory J. Berkland, Piyoosh A. Sharma, Meredith E. Jackrel, Mark Andrew White, Jai S. Rudra
This study examines how substituents on benzyl groups affect self-assembly and immunogenicity of amphipathic peptides, showing that chemical modifications influence fibril formation and immune responses.
Advanced Science · Jan 20, 2026Peer-reviewedBioengineering