Zeran Lin

This study investigates the role of Wisp1 in glucose homeostasis using Wisp1 knockout mice, finding improved insulin sensitivity and reduced adipose inflammation but no effect on whole-body glucose tolerance.

Adipocyte-specific deletion of Prdm16 ablates beige fat identity, derepresses the secreted enzyme Qsox1, and induces vascular fibrosis, angiotensin II hyperreactivity, and elevated blood pressure in mice.