Jacek Gaertig

This study shows that SPEF1 stabilizes central microtubules in Tetrahymena cilia, with defects in its absence affecting ciliary structure and function.

The paper investigates how left-right cortical interactions drive pattern formation in Tetrahymena by analyzing the role of HPO1 and Bcd1 in oral apparatus positioning.

The paper identifies JanA, a Polo kinase in Tetrahymena, whose loss causes a dorsal/ventral intracellular homeosis by altering organelle positioning and cortical patterning.

The paper presents a high-resolution structure of the ciliary tip central pair in Tetrahymena thermophila and identifies proteins that stabilize microtubules.

DomainFit identifies protein domains in low-resolution cryo-EM maps using AlphaFold2 models, revealing new proteins in cellular complexes.