Author

Aparna Thulasidharan

Indian Institute of Science Education and Research PuneORCID 0000-0003-4428-3308Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Girish S. RatnaparkhiiD· 3 shared Lovleen GargiD· 2 shared Shweta TendulkariD· 2 shared Amarendranath SooryiD· 1 shared Anuradha RatnaparkhiiD· 1 shared Bhagyashree KaduskariD· 1 shared Namrata Pramod KulkarniiD· 1 shared Pulkit GoeliD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Girish S. RatnaparkhiORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 3, 2026

Fos regulates age-dependent neuroinflammation in VAPBALS

Namrata Pramod Kulkarni, Aparna Thulasidharan, Amarendranath Soory…·Girish S. Ratnaparkhi

The paper identifies Fos as a regulator of age-dependent neuroinflammation in a Drosophila model of ALS8, showing its role in modulating inflammation and motor function.

DOI 10.64898/2026.02.28.708780

Drosophilabulk RNA-seq

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NeuroscienceNeurobiology of DiseasePeer-reviewedApr 26, 2024

Age-dependent dynamics of neuronal VAPBALS inclusions in the adult brain

Aparna Thulasidharan, Lovleen Garg, Shweta Tendulkar, Girish S. Ratnaparkhi

This study investigates age-dependent changes in neuronal VAPBALS inclusions in a Drosophila ALS model, showing autophagy's role in aggregate clearance and the impact of TER94 on inclusion density.

12 citations

Drosophilaexperimental assay

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GeneticsbioRxivPreprintApr 7, 2021

Caspar, an adapter for VAP and TER94, delays the progression of disease by regulating glial inflammation in a Drosophila model of ALS8

Shweta Tendulkar, Sushmitha Hegde, Aparna Thulasidharan…·Girish S. Ratnaparkhi

The paper shows that Caspar overexpression in glia slows ALS progression by reducing inflammation in a Drosophila model.

1 citation

Drosophilaexperimental assay

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