Simon J. Charnock

The paper develops a microfluidic screening platform to identify sialic acid-active enzymes in metagenomes, discovering a new aldolase enzyme from garden soil.

This paper introduces a bi-level diversity-optimization framework for selecting representative protein panels, reducing redundancy and improving diversity compared to existing methods.

This paper introduces ro-crate-rs, a Rust library for creating RO-Crates to manage synthetic biology data, enabling FAIR compliance and reproducibility in automated workflows.

This paper develops a thermostable in vitro transcription-translation system using Thermus thermophilus extracts for enzyme screening in microdroplets.

The paper introduces Coevolution Similarity Networks (CSNs) to analyze enzyme families by clustering based on coevolution patterns, showing higher predictive power for substrate specificity annotation than Sequence Similarity Networks.