Jeongho Lee

This paper evaluates combining expression-based surrogate variables and genotype-based principal components in differential expression analysis, finding the combined approach improves replicability and biological recall in ALS datasets.

The paper shows that TOP2B and DNA-PK regulate hypoxia-inducible gene expression through DNA topology changes, with DNA-PK phosphorylating TOP2B to control its activity.

This study shows that Lactiplantibacillus plantarum K8 lysates suppress hypoxia-induced gene expression by reducing HIF1 accumulation and its target genes.